“What nasal spray is best for a sinus infection?”

Flonase, which contains fluticasone, reduces swelling in the nasal passages. Nasacort also is a good nasal spray however, they require a prescription. OTC decongestant nasal sprays work well too such as Afrin and Neo-Synephrine. These nasal sprays should not be used more than 3-5 days since they cause rebound effects. In other words, they will cause swelling if you too frequently.