“Is it safe to take 600mg of seroquel at one time?”

Depending on the condition being treated, the maximum recommended dose of quetiapine (trade name Seroquel) is 800 mg/day. Lower doses and/or monitoring may be necessary with that combination of medications though. Quetiapine, gabapentin, and valerian together can increase your risk of experiencing severe drowsiness, dizziness, and/or confusion. Quetiapine and ondansetron (trade name Zofran) together can increase your risk for irregular heart rhythms. Check with your doctor and/or pharmacist about your specific doses and conditions.